7And to you who are troubled rest with us, when the Lord Jesus shall be revealed from heaven with his mighty angels,

8In flaming fire taking vengeance on them that know not God, and that obey not the gospel of our Lord Jesus Christ:

9Who shall be punished with everlasting destruction from the presence of the Lord, and from the glory of his power;

10When he shall come to be glorified in his saints, and to be admired in all them that believe (because our testimony among you was believed) in that day.

Obviously it is the apostate jews that are causing the trouble so its easy to see them as being on the wrong end of the 'flaming fire'.
Probably this fire;

But when the king heard thereof, he was wroth: and he sent forth his armies, and destroyed those murderers, and burned up their city.

There is every reason to believe the judgment against the apostates has historical as well as eternal aspects. The prophecies that Jesus personally made against Israel have yet, at the time, come to pass. When they do there can be no doubt that He as a true prophet and is in heaven , and thats not too far off.

I dont believe the Second Advent is in view here.